Richard James

Associate Professor

Seattle Childrens Research Institute

Cell Signaling & Cell/Environment Interactions

Genetics, Genomics & Evolution

Microbiology, Infection & Immunity

Engineering B cells to understand the genetics of immune disease and to build therapies

Faculty Contact Information

Building: 1900 9th ave Jack Macdonald Building Room: 639 Box: JMB-6 Phone: 206-884-3290

Research Summary

The goal of the James lab is to learn how human B cells normally differentiate into long-lived antibody-secreting plasma cells. We would like to better understand how B cell differentiation becomes dysregulated and contributes to disease, including lymphoma, primary immune deficiency and lupus. Ultimately, we will use what we learn to inform diagnoses of B cell related disease and to develop B cell-based therapies.

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PubMed Collection Link

Accepting Students For:

Rotation, Spring
Rotation, Summer

Lab Information

Location: Seattle Children's Research Institute
Building: Jack Macdonald Building
Room: 639
Phone: 206-884-3290