faculty

Nic Lehrbach

nlehrbach@fredhutch.org
Assistant Professor

Fred Hutch

Cell Signaling & Cell/Environment Interactions

Developmental Biology, Stem Cells & Aging

Gene Expression, Cell Cycle & Chromosome Biology

Regulation of protein degradation

Faculty Contact Information

Building: Weintraub Building Room: B2-175 Box: A2-025 Phone: 206-667-1576 https://research.fredhutch.org/lehrbach/en.html

Research Summary

Impaired proteasome function results in accumulation of damaged and misfolded proteins, which causes cellular dysfunction in aging, neurodegeneration, and many rare genetic diseases. My lab aims to understand how the proteasome is regulated, with the long-term goal of finding new treatments for these diseases. We take a forward genetic approach in C. elegans to discover regulators of the proteasome, and we use a range of genetic, molecular/cell biology, biochemical and genomic techniques to reveal the mechanisms by which they function.

Training Summary

2021: Fred Hutch Faculty Leadership Incubator
2021: Fred Hutch Bias Mitigation Education

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&query_key=1&WebEnv=MCID_614de58807d6dc4dbf5d801b&retmode=json
Resource id #567 -- array(2) { ["header"]=> array(2) { ["type"]=> string(8) "esummary" ["version"]=> string(3) "0.3" } ["result"]=> array(22) { ["uids"]=> array(21) { [0]=> string(8) "34329465" [1]=> string(8) "31002798" [2]=> string(8) "30973820" [3]=> string(8) "30287474" [4]=> string(8) "28060408" [5]=> string(8) "27528192" [6]=> string(8) "25811365" [7]=> string(8) "24137537" [8]=> string(8) "23475189" [9]=> string(8) "23097426" [10]=> string(8) "22738725" [11]=> string(8) "22700655" [12]=> string(8) "21815640" [13]=> string(8) "21755474" [14]=> string(8) "20835247" [15]=> string(8) "20421599" [16]=> string(8) "21627031" [17]=> string(8) "19713957" [18]=> string(8) "18571451" [19]=> string(8) "18565984" [20]=> string(8) "15520464" } [34329465]=> array(43) { ["uid"]=> string(8) "34329465" ["pubdate"]=> string(10) "2021 Sep 7" ["epubdate"]=> string(0) "" ["source"]=> string(17) "Nucleic Acids Res" ["authors"]=> array(14) { [0]=> array(3) { ["name"]=> string(15) "Charlesworth AG" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(10) "Seroussi U" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(9) "Renaud MS" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(9) "Sundby AE" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(9) "Molnar RI" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(6) "Lao RX" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(9) "Willis AR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(8) "Woock JR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(7) "Aber MJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [10]=> array(3) { ["name"]=> string(7) "Diao AJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [11]=> array(3) { ["name"]=> string(9) "Reinke AW" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [12]=> array(3) { ["name"]=> string(8) "Ruvkun G" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [13]=> array(3) { ["name"]=> string(11) "Claycomb JM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(11) "Claycomb JM" ["title"]=> string(108) "Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility." ["sorttitle"]=> string(106) "two isoforms of the essential c elegans argonaute csr 1 differentially regulate sperm and oocyte fertility" ["volume"]=> string(2) "49" ["issue"]=> string(2) "15" ["pages"]=> string(9) "8836-8865" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0411011" ["issn"]=> string(9) "0305-1048" ["essn"]=> string(9) "1362-4962" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "4" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "34329465" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(7) "6331683" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(19) "10.1093/nar/gkab619" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC8421154" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "34329465" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "34329465" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC8421154;" } } ["history"]=> array(6) { [0]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2021/07/19 00:00" } [1]=> array(2) { ["pubstatus"]=> string(7) "revised" ["date"]=> string(16) "2021/07/01 00:00" } [2]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2020/08/03 00:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2021/07/31 06:00" } [4]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2021/09/11 06:00" } [5]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2021/07/30 17:28" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> string(0) "" ["fulljournalname"]=> string(22) "Nucleic acids research" ["elocationid"]=> string(24) "doi: 10.1093/nar/gkab619" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2021/09/07 00:00" ["sortfirstauthor"]=> string(15) "Charlesworth AG" ["vernaculartitle"]=> string(0) "" } [31002798]=> array(43) { ["uid"]=> string(8) "31002798" ["pubdate"]=> string(11) "2019 Apr 18" ["epubdate"]=> string(0) "" ["source"]=> string(4) "Cell" ["authors"]=> array(3) { [0]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(8) "Breen PC" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(8) "Ruvkun G" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Ruvkun G" ["title"]=> string(99) "Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression." ["sorttitle"]=> string(98) "protein sequence editing of skn 1a nrf1 by peptide n glycanase controls proteasome gene expression" ["volume"]=> string(3) "177" ["issue"]=> string(1) "3" ["pages"]=> string(11) "737-750.e15" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0413066" ["issn"]=> string(9) "0092-8674" ["essn"]=> string(9) "1097-4172" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "4" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "31002798" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(21) "S0092-8674(19)30336-8" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(26) "10.1016/j.cell.2019.03.035" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC6574124" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(12) "NIHMS1525118" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "31002798" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "31002798" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(47) "pmc-id: PMC6574124;manuscript-id: NIHMS1525118;" } } ["history"]=> array(6) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2018/08/24 00:00" } [1]=> array(2) { ["pubstatus"]=> string(7) "revised" ["date"]=> string(16) "2018/12/14 00:00" } [2]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2019/03/15 00:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2019/04/20 06:00" } [4]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2019/04/20 06:00" } [5]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2020/01/16 06:00" } } ["references"]=> array(1) { [0]=> array(4) { ["refsource"]=> string(45) "Nat Rev Mol Cell Biol. 2019 Jun;20(6):324-325" ["reftype"]=> string(10) "Comment in" ["pmid"]=> int(31053827) ["note"]=> string(0) "" } } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(25) ["fulljournalname"]=> string(4) "Cell" ["elocationid"]=> string(31) "doi: 10.1016/j.cell.2019.03.035" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2019/04/18 00:00" ["sortfirstauthor"]=> string(11) "Lehrbach NJ" ["vernaculartitle"]=> string(0) "" } [30973820]=> array(43) { ["uid"]=> string(8) "30973820" ["pubdate"]=> string(11) "2019 Apr 11" ["epubdate"]=> string(11) "2019 Apr 11" ["source"]=> string(5) "Elife" ["authors"]=> array(2) { [0]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(8) "Ruvkun G" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Ruvkun G" ["title"]=> string(117) "Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity." ["sorttitle"]=> string(116) "endoplasmic reticulum associated skn 1a nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity" ["volume"]=> string(1) "8" ["issue"]=> string(0) "" ["pages"]=> string(0) "" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101579614" ["issn"]=> string(0) "" ["essn"]=> string(9) "2050-084X" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "3" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "30973820" } [1]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(19) "10.7554/eLife.44425" } [2]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(5) "44425" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC6459674" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "30973820" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "30973820" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC6459674;" } } ["history"]=> array(5) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2018/12/19 00:00" } [1]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2019/03/29 00:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2019/04/12 06:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2019/04/12 06:00" } [4]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2020/03/12 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(12) ["fulljournalname"]=> string(5) "eLife" ["elocationid"]=> string(37) "pii: e44425. doi: 10.7554/eLife.44425" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2019/04/11 00:00" ["sortfirstauthor"]=> string(11) "Lehrbach NJ" ["vernaculartitle"]=> string(0) "" } [30287474]=> array(43) { ["uid"]=> string(8) "30287474" ["pubdate"]=> string(8) "2018 Dec" ["epubdate"]=> string(10) "2018 Oct 4" ["source"]=> string(8) "Genetics" ["authors"]=> array(8) { [0]=> array(3) { ["name"]=> string(10) "Tillman EJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(13) "Richardson CE" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(9) "Cattie DJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(8) "Reddy KC" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(8) "Droste R" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(8) "Ruvkun G" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(6) "Kim DH" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(6) "Kim DH" ["title"]=> string(140) "Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of Caenorhabditis elegans." ["sorttitle"]=> string(136) "endoplasmic reticulum homeostasis is modulated by the forkhead transcription factor fkh 9 during infection of i caenorhabditis elegans i" ["volume"]=> string(3) "210" ["issue"]=> string(1) "4" ["pages"]=> string(9) "1329-1337" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0374636" ["issn"]=> string(9) "0016-6731" ["essn"]=> string(9) "1943-2631" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "30287474" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(19) "genetics.118.301450" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(27) "10.1534/genetics.118.301450" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC6283152" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "30287474" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "30287474" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC6283152;" } } ["history"]=> array(5) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2018/08/01 00:00" } [1]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2018/09/25 00:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2018/10/06 06:00" } [3]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2019/02/27 06:00" } [4]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2018/10/06 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(4) ["fulljournalname"]=> string(8) "Genetics" ["elocationid"]=> string(32) "doi: 10.1534/genetics.118.301450" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2018/12/01 00:00" ["sortfirstauthor"]=> string(10) "Tillman EJ" ["vernaculartitle"]=> string(0) "" } [28060408]=> array(43) { ["uid"]=> string(8) "28060408" ["pubdate"]=> string(10) "2017 Jan 5" ["epubdate"]=> string(10) "2017 Jan 5" ["source"]=> string(20) "Curr Protoc Mol Biol" ["authors"]=> array(3) { [0]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(4) "Ji F" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(10) "Sadreyev R" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(10) "Sadreyev R" ["title"]=> string(97) "Next-Generation Sequencing for Identification of EMS-Induced Mutations in Caenorhabditis elegans." ["sorttitle"]=> string(96) "next generation sequencing for identification of ems induced mutations in caenorhabditis elegans" ["volume"]=> string(3) "117" ["issue"]=> string(0) "" ["pages"]=> string(14) "7.29.1-7.29.12" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "8908160" ["issn"]=> string(9) "1934-3639" ["essn"]=> string(9) "1934-3647" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "3" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "28060408" } [1]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(15) "10.1002/cpmb.27" } [2]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC5303615" } [3]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(11) "NIHMS820501" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "28060408" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "28060408" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(46) "pmc-id: PMC5303615;manuscript-id: NIHMS820501;" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2017/01/07 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2017/01/07 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2017/11/14 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(8) ["fulljournalname"]=> string(38) "Current protocols in molecular biology" ["elocationid"]=> string(20) "doi: 10.1002/cpmb.27" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2017/01/05 00:00" ["sortfirstauthor"]=> string(11) "Lehrbach NJ" ["vernaculartitle"]=> string(0) "" } [27528192]=> array(43) { ["uid"]=> string(8) "27528192" ["pubdate"]=> string(11) "2016 Aug 16" ["epubdate"]=> string(11) "2016 Aug 16" ["source"]=> string(5) "Elife" ["authors"]=> array(2) { [0]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(8) "Ruvkun G" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Ruvkun G" ["title"]=> string(89) "Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1." ["sorttitle"]=> string(88) "proteasome dysfunction triggers activation of skn 1a nrf1 by the aspartic protease ddi 1" ["volume"]=> string(1) "5" ["issue"]=> string(0) "" ["pages"]=> string(0) "" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101579614" ["issn"]=> string(0) "" ["essn"]=> string(9) "2050-084X" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "3" ["articleids"]=> array(6) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "27528192" } [1]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(19) "10.7554/eLife.17721" } [2]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC4987142" } [3]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "27528192" } [4]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "27528192" } [5]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC4987142;" } } ["history"]=> array(5) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2016/05/11 00:00" } [1]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2016/07/19 00:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2016/08/17 06:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2016/08/17 06:00" } [4]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2017/10/31 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(76) ["fulljournalname"]=> string(5) "eLife" ["elocationid"]=> string(37) "pii: e17721. doi: 10.7554/eLife.17721" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2016/08/16 00:00" ["sortfirstauthor"]=> string(11) "Lehrbach NJ" ["vernaculartitle"]=> string(0) "" } [25811365]=> array(43) { ["uid"]=> string(8) "25811365" ["pubdate"]=> string(8) "2015 Mar" ["epubdate"]=> string(11) "2015 Mar 26" ["source"]=> string(10) "PLoS Genet" ["authors"]=> array(4) { [0]=> array(3) { ["name"]=> string(13) "Sapetschnig A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(9) "Sarkies P" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Miska EA" ["title"]=> string(51) "Tertiary siRNAs mediate paramutation in C. elegans." ["sorttitle"]=> string(49) "tertiary sirnas mediate paramutation in c elegans" ["volume"]=> string(2) "11" ["issue"]=> string(1) "3" ["pages"]=> string(8) "e1005078" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101239074" ["issn"]=> string(9) "1553-7390" ["essn"]=> string(9) "1553-7404" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "258" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "25811365" } [1]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(28) "10.1371/journal.pgen.1005078" } [2]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(20) "PGENETICS-D-14-01476" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC4374809" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "25811365" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "25811365" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC4374809;" } } ["history"]=> array(5) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2014/06/04 00:00" } [1]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2015/02/17 00:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2015/03/27 06:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2015/03/27 06:00" } [4]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2015/12/29 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(33) ["fulljournalname"]=> string(13) "PLoS genetics" ["elocationid"]=> string(33) "doi: 10.1371/journal.pgen.1005078" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2015/03/26 00:00" ["sortfirstauthor"]=> string(13) "Sapetschnig A" ["vernaculartitle"]=> string(0) "" } [24137537]=> array(43) { ["uid"]=> string(8) "24137537" ["pubdate"]=> string(10) "2013 Oct 8" ["epubdate"]=> string(10) "2013 Oct 8" ["source"]=> string(5) "Elife" ["authors"]=> array(8) { [0]=> array(3) { ["name"]=> string(6) "Ashe A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(11) "Bélicard T" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(8) "Le Pen J" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(9) "Sarkies P" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(9) "Frézal L" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(9) "Félix MA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Miska EA" ["title"]=> string(117) "A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity." ["sorttitle"]=> string(114) "deletion polymorphism in the caenorhabditis elegans rig i homolog disables viral rna dicing and antiviral immunity" ["volume"]=> string(1) "2" ["issue"]=> string(0) "" ["pages"]=> string(6) "e00994" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101579614" ["issn"]=> string(0) "" ["essn"]=> string(9) "2050-084X" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "3" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "24137537" } [1]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(19) "10.7554/eLife.00994" } [2]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(5) "00994" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC3793227" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "24137537" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "24137537" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC3793227;" } } ["history"]=> array(5) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2013/05/24 00:00" } [1]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2013/08/20 00:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2013/10/19 06:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2013/10/19 06:00" } [4]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2013/10/19 06:01" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(62) ["fulljournalname"]=> string(5) "eLife" ["elocationid"]=> string(24) "doi: 10.7554/eLife.00994" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2013/10/08 00:00" ["sortfirstauthor"]=> string(6) "Ashe A" ["vernaculartitle"]=> string(0) "" } [23475189]=> array(43) { ["uid"]=> string(8) "23475189" ["pubdate"]=> string(8) "2013 Jul" ["epubdate"]=> string(11) "2013 Mar 11" ["source"]=> string(11) "Mol Biosyst" ["authors"]=> array(6) { [0]=> array(3) { ["name"]=> string(8) "Castro C" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(10) "Krumsiek J" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(10) "Murfitt SA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(10) "Griffin JL" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(10) "Griffin JL" ["title"]=> string(102) "A study of Caenorhabditis elegans DAF-2 mutants by metabolomics and differential correlation networks." ["sorttitle"]=> string(99) "study of caenorhabditis elegans daf 2 mutants by metabolomics and differential correlation networks" ["volume"]=> string(1) "9" ["issue"]=> string(1) "7" ["pages"]=> string(7) "1632-42" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101251620" ["issn"]=> string(9) "1742-206X" ["essn"]=> string(9) "1742-2051" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "23475189" } [1]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(18) "10.1039/c3mb25539e" } [2]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC7002165" } [3]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(8) "EMS85664" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "23475189" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "23475189" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(43) "pmc-id: PMC7002165;manuscript-id: EMS85664;" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2013/03/12 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2013/03/12 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2014/01/01 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(19) ["fulljournalname"]=> string(20) "Molecular bioSystems" ["elocationid"]=> string(23) "doi: 10.1039/c3mb25539e" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2013/07/01 00:00" ["sortfirstauthor"]=> string(8) "Castro C" ["vernaculartitle"]=> string(0) "" } [23097426]=> array(43) { ["uid"]=> string(8) "23097426" ["pubdate"]=> string(8) "2012 Dec" ["epubdate"]=> string(11) "2012 Oct 24" ["source"]=> string(3) "RNA" ["authors"]=> array(6) { [0]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(8) "Castro C" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(10) "Murfitt KJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(15) "Abreu-Goodger C" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(10) "Griffin JL" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Miska EA" ["title"]=> string(147) "Post-developmental microRNA expression is required for normal physiology, and regulates aging in parallel to insulin/IGF-1 signaling in C. elegans." ["sorttitle"]=> string(144) "post developmental microrna expression is required for normal physiology and regulates aging in parallel to insulin igf 1 signaling in c elegans" ["volume"]=> string(2) "18" ["issue"]=> string(2) "12" ["pages"]=> string(7) "2220-35" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "9509184" ["issn"]=> string(9) "1355-8382" ["essn"]=> string(9) "1469-9001" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "23097426" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(14) "rna.035402.112" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(22) "10.1261/rna.035402.112" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC3504673" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "23097426" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "23097426" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC3504673;" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2012/10/26 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2012/10/26 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2013/02/01 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(21) ["fulljournalname"]=> string(20) "RNA (New York, N.Y.)" ["elocationid"]=> string(27) "doi: 10.1261/rna.035402.112" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2012/12/01 00:00" ["sortfirstauthor"]=> string(11) "Lehrbach NJ" ["vernaculartitle"]=> string(0) "" } [22738725]=> array(43) { ["uid"]=> string(8) "22738725" ["pubdate"]=> string(10) "2012 Jul 6" ["epubdate"]=> string(11) "2012 Jun 25" ["source"]=> string(4) "Cell" ["authors"]=> array(15) { [0]=> array(3) { ["name"]=> string(6) "Ashe A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(13) "Sapetschnig A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(8) "Weick EM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(10) "Mitchell J" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(9) "Bagijn MP" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(10) "Cording AC" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(10) "Doebley AL" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(12) "Goldstein LD" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(8) "Le Pen J" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [10]=> array(3) { ["name"]=> string(11) "Pintacuda G" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [11]=> array(3) { ["name"]=> string(11) "Sakaguchi A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [12]=> array(3) { ["name"]=> string(9) "Sarkies P" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [13]=> array(3) { ["name"]=> string(7) "Ahmed S" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [14]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Miska EA" ["title"]=> string(87) "piRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegans." ["sorttitle"]=> string(85) "pirnas can trigger a multigenerational epigenetic memory in the germline of c elegans" ["volume"]=> string(3) "150" ["issue"]=> string(1) "1" ["pages"]=> string(5) "88-99" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0413066" ["issn"]=> string(9) "0092-8674" ["essn"]=> string(9) "1097-4172" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "22738725" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(21) "S0092-8674(12)00769-6" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(26) "10.1016/j.cell.2012.06.018" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC3464430" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "22738725" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "22738725" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC3464430;" } } ["history"]=> array(6) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2012/06/11 00:00" } [1]=> array(2) { ["pubstatus"]=> string(7) "revised" ["date"]=> string(16) "2012/06/18 00:00" } [2]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2012/06/18 00:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2012/06/29 06:00" } [4]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2012/06/29 06:00" } [5]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2012/09/20 06:00" } } ["references"]=> array(2) { [0]=> array(4) { ["refsource"]=> string(35) "Nat Rev Genet. 2012 Aug;13(8):518-9" ["reftype"]=> string(10) "Comment in" ["pmid"]=> int(22777129) ["note"]=> string(0) "" } [1]=> array(4) { ["refsource"]=> string(41) "Nat Rev Mol Cell Biol. 2012 Aug;13(8):477" ["reftype"]=> string(10) "Comment in" ["pmid"]=> int(22820881) ["note"]=> string(0) "" } } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(262) ["fulljournalname"]=> string(4) "Cell" ["elocationid"]=> string(31) "doi: 10.1016/j.cell.2012.06.018" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2012/07/06 00:00" ["sortfirstauthor"]=> string(6) "Ashe A" ["vernaculartitle"]=> string(0) "" } [22700655]=> array(43) { ["uid"]=> string(8) "22700655" ["pubdate"]=> string(10) "2012 Aug 3" ["epubdate"]=> string(11) "2012 Jun 14" ["source"]=> string(7) "Science" ["authors"]=> array(8) { [0]=> array(3) { ["name"]=> string(9) "Bagijn MP" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(12) "Goldstein LD" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(13) "Sapetschnig A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(8) "Weick EM" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(10) "Bouasker S" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(9) "Simard MJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Miska EA" ["title"]=> string(66) "Function, targets, and evolution of Caenorhabditis elegans piRNAs." ["sorttitle"]=> string(63) "function targets and evolution of caenorhabditis elegans pirnas" ["volume"]=> string(3) "337" ["issue"]=> string(4) "6094" ["pages"]=> string(7) "574-578" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0404511" ["issn"]=> string(9) "0036-8075" ["essn"]=> string(9) "1095-9203" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "22700655" } [1]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(23) "10.1126/science.1220952" } [2]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC3951736" } [3]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(8) "EMS57182" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "22700655" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "22700655" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(43) "pmc-id: PMC3951736;manuscript-id: EMS57182;" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2012/06/16 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2012/06/16 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2012/09/15 06:00" } } ["references"]=> array(3) { [0]=> array(4) { ["refsource"]=> string(35) "Nat Rev Genet. 2012 Aug;13(8):518-9" ["reftype"]=> string(10) "Comment in" ["pmid"]=> int(22777129) ["note"]=> string(0) "" } [1]=> array(4) { ["refsource"]=> string(41) "Nat Rev Mol Cell Biol. 2012 Aug;13(8):477" ["reftype"]=> string(10) "Comment in" ["pmid"]=> int(22820881) ["note"]=> string(0) "" } [2]=> array(4) { ["refsource"]=> string(36) "Science. 2012 Aug 3;337(6094):529-30" ["reftype"]=> string(10) "Comment in" ["pmid"]=> int(22859473) ["note"]=> string(0) "" } } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(157) ["fulljournalname"]=> string(24) "Science (New York, N.Y.)" ["elocationid"]=> string(28) "doi: 10.1126/science.1220952" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2012/08/03 00:00" ["sortfirstauthor"]=> string(9) "Bagijn MP" ["vernaculartitle"]=> string(0) "" } [21815640]=> array(43) { ["uid"]=> string(8) "21815640" ["pubdate"]=> string(10) "2011 Sep 6" ["epubdate"]=> string(11) "2011 Aug 11" ["source"]=> string(12) "Biochemistry" ["authors"]=> array(6) { [0]=> array(3) { ["name"]=> string(12) "Lightfoot HL" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(8) "Bugaut A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(9) "Armisen J" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(17) "Balasubramanian S" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(17) "Balasubramanian S" ["title"]=> string(85) "A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing." ["sorttitle"]=> string(82) "lin28 dependent structural change in pre let 7g directly inhibits dicer processing" ["volume"]=> string(2) "50" ["issue"]=> string(2) "35" ["pages"]=> string(7) "7514-21" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0370623" ["issn"]=> string(9) "0006-2960" ["essn"]=> string(9) "1520-4995" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "21815640" } [1]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(17) "10.1021/bi200851d" } [2]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC3361669" } [3]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(9) "UKMS47976" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "21815640" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "21815640" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(44) "pmc-id: PMC3361669;manuscript-id: UKMS47976;" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2011/08/06 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2011/08/06 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2011/10/22 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(25) ["fulljournalname"]=> string(12) "Biochemistry" ["elocationid"]=> string(22) "doi: 10.1021/bi200851d" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2011/09/06 00:00" ["sortfirstauthor"]=> string(12) "Lightfoot HL" ["vernaculartitle"]=> string(0) "" } [21755474]=> array(43) { ["uid"]=> string(8) "21755474" ["pubdate"]=> string(4) "2011" ["epubdate"]=> string(0) "" ["source"]=> string(16) "Adv Exp Med Biol" ["authors"]=> array(2) { [0]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Miska EA" ["title"]=> string(35) "Regulation of pre-miRNA Processing." ["sorttitle"]=> string(34) "regulation of pre mirna processing" ["volume"]=> string(3) "700" ["issue"]=> string(0) "" ["pages"]=> string(5) "67-75" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0121103" ["issn"]=> string(9) "0065-2598" ["essn"]=> string(9) "2214-8019" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "4" ["articleids"]=> array(4) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "21755474" } [1]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(27) "10.1007/978-1-4419-7823-3_7" } [2]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "21755474" } [3]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "21755474" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2011/07/15 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2011/07/15 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2016/04/24 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(4) ["fulljournalname"]=> string(45) "Advances in experimental medicine and biology" ["elocationid"]=> string(0) "" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2011/01/01 00:00" ["sortfirstauthor"]=> string(11) "Lehrbach NJ" ["vernaculartitle"]=> string(0) "" } [20835247]=> array(43) { ["uid"]=> string(8) "20835247" ["pubdate"]=> string(8) "2010 Oct" ["epubdate"]=> string(11) "2010 Sep 12" ["source"]=> string(11) "Nat Methods" ["authors"]=> array(15) { [0]=> array(3) { ["name"]=> string(11) "Jovanovic M" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(8) "Reiter L" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(9) "Picotti P" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(7) "Lange V" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(7) "Bogan E" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(12) "Hurschler BA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(11) "Blenkiron C" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(7) "Ding XC" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(7) "Weiss M" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [10]=> array(3) { ["name"]=> string(11) "Schrimpf SP" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [11]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [12]=> array(3) { ["name"]=> string(11) "Grosshans H" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [13]=> array(3) { ["name"]=> string(11) "Aebersold R" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [14]=> array(3) { ["name"]=> string(13) "Hengartner MO" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(13) "Hengartner MO" ["title"]=> string(97) "A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans." ["sorttitle"]=> string(93) "quantitative targeted proteomics approach to validate predicted microrna targets in c elegans" ["volume"]=> string(1) "7" ["issue"]=> string(2) "10" ["pages"]=> string(6) "837-42" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101215604" ["issn"]=> string(9) "1548-7091" ["essn"]=> string(9) "1548-7105" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "20835247" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(10) "nmeth.1504" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(18) "10.1038/nmeth.1504" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC3444237" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(9) "UKMS49182" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "20835247" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "20835247" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(44) "pmc-id: PMC3444237;manuscript-id: UKMS49182;" } } ["history"]=> array(5) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2010/01/26 00:00" } [1]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2010/08/23 00:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2010/09/14 06:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2010/09/14 06:00" } [4]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2010/10/23 06:00" } } ["references"]=> array(2) { [0]=> array(4) { ["refsource"]=> string(33) "Nat Methods. 2010 Oct;7(10):795-7" ["reftype"]=> string(10) "Comment in" ["pmid"]=> int(20885440) ["note"]=> string(0) "" } [1]=> array(4) { ["refsource"]=> string(43) "Expert Rev Proteomics. 2011 Apr;8(2):149-52" ["reftype"]=> string(10) "Comment in" ["pmid"]=> int(21501007) ["note"]=> string(0) "" } } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(28) ["fulljournalname"]=> string(14) "Nature methods" ["elocationid"]=> string(23) "doi: 10.1038/nmeth.1504" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2010/10/01 00:00" ["sortfirstauthor"]=> string(11) "Jovanovic M" ["vernaculartitle"]=> string(0) "" } [20421599]=> array(43) { ["uid"]=> string(8) "20421599" ["pubdate"]=> string(8) "2010 Jul" ["epubdate"]=> string(11) "2010 Apr 26" ["source"]=> string(8) "Genetics" ["authors"]=> array(4) { [0]=> array(3) { ["name"]=> string(7) "Shaw WR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(9) "Armisen J" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Miska EA" ["title"]=> string(136) "The conserved miR-51 microRNA family is redundantly required for embryonic development and pharynx attachment in Caenorhabditis elegans." ["sorttitle"]=> string(131) "conserved mir 51 microrna family is redundantly required for embryonic development and pharynx attachment in caenorhabditis elegans" ["volume"]=> string(3) "185" ["issue"]=> string(1) "3" ["pages"]=> string(7) "897-905" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0374636" ["issn"]=> string(9) "0016-6731" ["essn"]=> string(9) "1943-2631" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "20421599" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(19) "genetics.110.117515" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(27) "10.1534/genetics.110.117515" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC2900971" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "20421599" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "20421599" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(19) "pmc-id: PMC2900971;" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2010/04/28 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2010/04/28 06:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2010/11/17 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(34) ["fulljournalname"]=> string(8) "Genetics" ["elocationid"]=> string(32) "doi: 10.1534/genetics.110.117515" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2010/07/01 00:00" ["sortfirstauthor"]=> string(7) "Shaw WR" ["vernaculartitle"]=> string(0) "" } [21627031]=> array(43) { ["uid"]=> string(8) "21627031" ["pubdate"]=> string(4) "2010" ["epubdate"]=> string(0) "" ["source"]=> string(16) "Adv Exp Med Biol" ["authors"]=> array(2) { [0]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Miska EA" ["title"]=> string(35) "Regulation of pre-miRNA processing." ["sorttitle"]=> string(34) "regulation of pre mirna processing" ["volume"]=> string(3) "700" ["issue"]=> string(0) "" ["pages"]=> string(5) "67-75" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0121103" ["issn"]=> string(9) "0065-2598" ["essn"]=> string(9) "2214-8019" ["pubtype"]=> array(2) { [0]=> string(15) "Journal Article" [1]=> string(6) "Review" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(1) "4" ["articleids"]=> array(3) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "21627031" } [1]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "21627031" } [2]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "21627031" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2011/06/02 06:00" } [1]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2010/01/01 00:00" } [2]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2011/06/10 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(6) ["fulljournalname"]=> string(45) "Advances in experimental medicine and biology" ["elocationid"]=> string(0) "" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2010/01/01 00:00" ["sortfirstauthor"]=> string(11) "Lehrbach NJ" ["vernaculartitle"]=> string(0) "" } [19713957]=> array(43) { ["uid"]=> string(8) "19713957" ["pubdate"]=> string(8) "2009 Oct" ["epubdate"]=> string(11) "2009 Aug 27" ["source"]=> string(19) "Nat Struct Mol Biol" ["authors"]=> array(7) { [0]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(9) "Armisen J" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(12) "Lightfoot HL" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(10) "Murfitt KJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(8) "Bugaut A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(17) "Balasubramanian S" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Miska EA" ["title"]=> string(101) "LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans." ["sorttitle"]=> string(99) "lin 28 and the poly u polymerase pup 2 regulate let 7 microrna processing in caenorhabditis elegans" ["volume"]=> string(2) "16" ["issue"]=> string(2) "10" ["pages"]=> string(7) "1016-20" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101186374" ["issn"]=> string(9) "1545-9993" ["essn"]=> string(9) "1545-9985" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "19713957" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(9) "nsmb.1675" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(17) "10.1038/nsmb.1675" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC2988485" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(9) "UKMS31550" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "19713957" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "19713957" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(44) "pmc-id: PMC2988485;manuscript-id: UKMS31550;" } } ["history"]=> array(5) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2009/08/18 00:00" } [1]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2009/08/20 00:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2009/08/29 09:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2009/08/29 09:00" } [4]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2009/10/29 06:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(120) ["fulljournalname"]=> string(37) "Nature structural & molecular biology" ["elocationid"]=> string(22) "doi: 10.1038/nsmb.1675" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2009/10/01 00:00" ["sortfirstauthor"]=> string(11) "Lehrbach NJ" ["vernaculartitle"]=> string(0) "" } [18571451]=> array(43) { ["uid"]=> string(8) "18571451" ["pubdate"]=> string(11) "2008 Jul 11" ["epubdate"]=> string(11) "2008 Jun 19" ["source"]=> string(8) "Mol Cell" ["authors"]=> array(15) { [0]=> array(3) { ["name"]=> string(6) "Das PP" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(9) "Bagijn MP" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(12) "Goldstein LD" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(11) "Woolford JR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [4]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [5]=> array(3) { ["name"]=> string(13) "Sapetschnig A" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [6]=> array(3) { ["name"]=> string(10) "Buhecha HR" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [7]=> array(3) { ["name"]=> string(12) "Gilchrist MJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [8]=> array(3) { ["name"]=> string(7) "Howe KL" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [9]=> array(3) { ["name"]=> string(7) "Stark R" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [10]=> array(3) { ["name"]=> string(10) "Matthews N" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [11]=> array(3) { ["name"]=> string(11) "Berezikov E" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [12]=> array(3) { ["name"]=> string(10) "Ketting RF" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [13]=> array(3) { ["name"]=> string(9) "Tavaré S" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [14]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Miska EA" ["title"]=> string(135) "Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline." ["sorttitle"]=> string(134) "piwi and pirnas act upstream of an endogenous sirna pathway to suppress tc3 transposon mobility in the caenorhabditis elegans germline" ["volume"]=> string(2) "31" ["issue"]=> string(1) "1" ["pages"]=> string(5) "79-90" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "9802571" ["issn"]=> string(9) "1097-2765" ["essn"]=> string(9) "1097-4164" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(8) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "18571451" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(21) "S1097-2765(08)00392-4" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(28) "10.1016/j.molcel.2008.06.003" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(10) "PMC3353317" } [4]=> array(3) { ["idtype"]=> string(3) "mid" ["idtypen"]=> int(8) ["value"]=> string(9) "UKMS47833" } [5]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "18571451" } [6]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "18571451" } [7]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(44) "pmc-id: PMC3353317;manuscript-id: UKMS47833;" } } ["history"]=> array(6) { [0]=> array(2) { ["pubstatus"]=> string(8) "received" ["date"]=> string(16) "2007/12/21 00:00" } [1]=> array(2) { ["pubstatus"]=> string(7) "revised" ["date"]=> string(16) "2008/06/01 00:00" } [2]=> array(2) { ["pubstatus"]=> string(8) "accepted" ["date"]=> string(16) "2008/06/09 00:00" } [3]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2008/06/24 09:00" } [4]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2008/08/05 09:00" } [5]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2008/06/24 09:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(189) ["fulljournalname"]=> string(14) "Molecular cell" ["elocationid"]=> string(33) "doi: 10.1016/j.molcel.2008.06.003" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2008/07/11 00:00" ["sortfirstauthor"]=> string(6) "Das PP" ["vernaculartitle"]=> string(0) "" } [18565984]=> array(43) { ["uid"]=> string(8) "18565984" ["pubdate"]=> string(8) "2008 May" ["epubdate"]=> string(11) "2008 Jun 19" ["source"]=> string(29) "Brief Funct Genomic Proteomic" ["authors"]=> array(2) { [0]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(8) "Miska EA" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(8) "Miska EA" ["title"]=> string(81) "Functional genomic, computational and proteomic analysis of C. elegans microRNAs." ["sorttitle"]=> string(78) "functional genomic computational and proteomic analysis of c elegans micrornas" ["volume"]=> string(1) "7" ["issue"]=> string(1) "3" ["pages"]=> string(6) "228-35" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(9) "101150306" ["issn"]=> string(9) "1473-9550" ["essn"]=> string(9) "1477-4062" ["pubtype"]=> array(2) { [0]=> string(15) "Journal Article" [1]=> string(6) "Review" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "256" ["articleids"]=> array(5) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "18565984" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(6) "eln024" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(19) "10.1093/bfgp/eln024" } [3]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "18565984" } [4]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "18565984" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2008/06/21 09:00" } [1]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2008/09/25 09:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2008/06/21 09:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(2) ["fulljournalname"]=> string(45) "Briefings in functional genomics & proteomics" ["elocationid"]=> string(24) "doi: 10.1093/bfgp/eln024" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2008/05/01 00:00" ["sortfirstauthor"]=> string(11) "Lehrbach NJ" ["vernaculartitle"]=> string(0) "" } [15520464]=> array(43) { ["uid"]=> string(8) "15520464" ["pubdate"]=> string(4) "2004" ["epubdate"]=> string(10) "2004 Nov 1" ["source"]=> string(17) "Nucleic Acids Res" ["authors"]=> array(4) { [0]=> array(3) { ["name"]=> string(8) "Druker R" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [1]=> array(3) { ["name"]=> string(10) "Bruxner TJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [2]=> array(3) { ["name"]=> string(11) "Lehrbach NJ" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } [3]=> array(3) { ["name"]=> string(10) "Whitelaw E" ["authtype"]=> string(6) "Author" ["clusterid"]=> string(0) "" } } ["lastauthor"]=> string(10) "Whitelaw E" ["title"]=> string(90) "Complex patterns of transcription at the insertion site of a retrotransposon in the mouse." ["sorttitle"]=> string(89) "complex patterns of transcription at the insertion site of a retrotransposon in the mouse" ["volume"]=> string(2) "32" ["issue"]=> string(2) "19" ["pages"]=> string(6) "5800-8" ["lang"]=> array(1) { [0]=> string(3) "eng" } ["nlmuniqueid"]=> string(7) "0411011" ["issn"]=> string(9) "0305-1048" ["essn"]=> string(9) "1362-4962" ["pubtype"]=> array(1) { [0]=> string(15) "Journal Article" } ["recordstatus"]=> string(28) "PubMed - indexed for MEDLINE" ["pubstatus"]=> string(3) "257" ["articleids"]=> array(7) { [0]=> array(3) { ["idtype"]=> string(6) "pubmed" ["idtypen"]=> int(1) ["value"]=> string(8) "15520464" } [1]=> array(3) { ["idtype"]=> string(3) "pii" ["idtypen"]=> int(4) ["value"]=> string(10) "32/19/5800" } [2]=> array(3) { ["idtype"]=> string(3) "doi" ["idtypen"]=> int(3) ["value"]=> string(18) "10.1093/nar/gkh914" } [3]=> array(3) { ["idtype"]=> string(3) "pmc" ["idtypen"]=> int(8) ["value"]=> string(9) "PMC528799" } [4]=> array(3) { ["idtype"]=> string(3) "rid" ["idtypen"]=> int(8) ["value"]=> string(8) "15520464" } [5]=> array(3) { ["idtype"]=> string(3) "eid" ["idtypen"]=> int(8) ["value"]=> string(8) "15520464" } [6]=> array(3) { ["idtype"]=> string(5) "pmcid" ["idtypen"]=> int(5) ["value"]=> string(18) "pmc-id: PMC528799;" } } ["history"]=> array(3) { [0]=> array(2) { ["pubstatus"]=> string(6) "pubmed" ["date"]=> string(16) "2004/11/03 09:00" } [1]=> array(2) { ["pubstatus"]=> string(7) "medline" ["date"]=> string(16) "2004/11/13 09:00" } [2]=> array(2) { ["pubstatus"]=> string(6) "entrez" ["date"]=> string(16) "2004/11/03 09:00" } } ["references"]=> array(0) { } ["attributes"]=> array(1) { [0]=> string(12) "Has Abstract" } ["pmcrefcount"]=> int(45) ["fulljournalname"]=> string(22) "Nucleic acids research" ["elocationid"]=> string(0) "" ["doctype"]=> string(8) "citation" ["srccontriblist"]=> array(0) { } ["booktitle"]=> string(0) "" ["medium"]=> string(0) "" ["edition"]=> string(0) "" ["publisherlocation"]=> string(0) "" ["publishername"]=> string(0) "" ["srcdate"]=> string(0) "" ["reportnumber"]=> string(0) "" ["availablefromurl"]=> string(0) "" ["locationlabel"]=> string(0) "" ["doccontriblist"]=> array(0) { } ["docdate"]=> string(0) "" ["bookname"]=> string(0) "" ["chapter"]=> string(0) "" ["sortpubdate"]=> string(16) "2004/11/01 00:00" ["sortfirstauthor"]=> string(8) "Druker R" ["vernaculartitle"]=> string(0) "" } } }

Publications

The following publications were retrieved from PubMed:

Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility.

Charlesworth AG, Seroussi U, Lehrbach NJ, Renaud MS, Sundby AE, Molnar RI, Lao RX, Willis AR, Woock JR, Aber MJ, Diao AJ, Reinke AW, Ruvkun G, Claycomb JM.

Nucleic Acids Res. 2021 Sep 7; 15(49)8836-8865

Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression.

Lehrbach NJ, Breen PC, Ruvkun G.

Cell. 2019 Apr 18; 3(177)737-750.e15

Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of Caenorhabditis elegans.

Tillman EJ, Richardson CE, Cattie DJ, Reddy KC, Lehrbach NJ, Droste R, Ruvkun G, Kim DH.

Genetics. 2018 Dec; 4(210)1329-1337

Next-Generation Sequencing for Identification of EMS-Induced Mutations in Caenorhabditis elegans.

Lehrbach NJ, Ji F, Sadreyev R.

Curr Protoc Mol Biol. 2017 Jan 5; (117)7.29.1-7.29.12



PubMed Collection Link

Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter
Permanent

Lab Information

Location: Fred Hutch
Building: Weintraub Building
Room: B2-175
Box: A2-025
Phone: 206-667-1576
https://research.fredhutch.org/lehrbach/en.html