faculty

Danny Miller

dm1@uw.edu
Assistant Professor

University of Washington

Laboratory Medicine and Pathology

Computational Biology

Gene Expression, Cell Cycle & Chromosome Biology

Genetics, Genomics & Evolution

Unsolved genetic disorders

Faculty Contact Information

Building: I Room: 607K Box: 356320

Research Summary

Danny E. Miller is an Assistant Professor at the University of Washington in the Departments of Pediatrics, Division of Genetic Medicine, and Laboratory Medicine & Pathology. Danny completed his medical and graduate work at the University of Kansas, in affiliation with the Stowers Institute for Medical Research, followed by a combined residency in Pediatrics and Medical Genetics at Seattle Children’s Hospital and the University of Washington. The mission of the Miller lab is to reduce the burden of undiagnosed genetic diseases on patients and their families by improving the efficiency and effectiveness of genetic testing, and to better understand human genetic disease through the identification and characterization of novel disease-causing variation. To do this, the Miller lab uses new technologies, such as long-read DNA and RNA sequencing to improve clinical genetic testing options and identify novel mechanisms of disease.

DEI Statement

The Miller Laboratory is committed to promoting diversity, equity, and inclusion in both our laboratory and clinical work. A diverse, equitable, and inclusive scientific community is a better one. We want to create opportunities for underrepresented scientists, amplify diverse voices, and help everyone meet their personal and professional goals.

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&query_key=1&WebEnv=MCID_6391549e471810761a23e355&retmode=json
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Publications

The following publications were retrieved from PubMed:

Paramutation-like Epigenetic Conversion by piRNA at the Telomere of Drosophila virilis.

Dorador AP, Dalikova M, Cerbin S, Stillman CM, Zych MG, Hawley RS, Miller DE, Ray DA, Funikov SY, Evgen'ev MB, Blumenstiel JP.

Biology (Basel). 2022 Oct 9; 10(11)

Targeted long-read sequencing identifies missing pathogenic variants in unsolved Werner syndrome cases.

Miller DE, Lee L, Galey M, Kandhaya-Pillai R, Tischkowitz M, Amalnath D, Vithlani A, Yokote K, Kato H, Maezawa Y, Takada-Watanabe A, Takemoto M, Martin GM, Eichler EE, Hisama FM, Oshima J.

J Med Genet. 2022 May 9; 11(59)1087-94

A complete reference genome improves analysis of human genetic variation.

Aganezov S, Yan SM, Soto DC, Kirsche M, Zarate S, Avdeyev P, Taylor DJ, Shafin K, Shumate A, Xiao C, Wagner J, McDaniel J, Olson ND, Sauria MEG, Vollger MR, Rhie A, Meredith M, Martin S, Lee J, Koren S, Rosenfeld JA, Paten B, Layer R, Chin CS, Sedlazeck FJ, Hansen NF, Miller DE, Phillippy AM, Miga KH, McCoy RC, Dennis MY, Zook JM, Schatz MC.

Science. 2022 Apr; 6588(376)eabl3533

The complete sequence of a human genome.

Nurk S, Koren S, Rhie A, Rautiainen M, Bzikadze AV, Mikheenko A, Vollger MR, Altemose N, Uralsky L, Gershman A, Aganezov S, Hoyt SJ, Diekhans M, Logsdon GA, Alonge M, Antonarakis SE, Borchers M, Bouffard GG, Brooks SY, Caldas GV, Chen NC, Cheng H, Chin CS, Chow W, de Lima LG, Dishuck PC, Durbin R, Dvorkina T, Fiddes IT, Formenti G, Fulton RS, Fungtammasan A, Garrison E, Grady PGS, Graves-Lindsay TA, Hall IM, Hansen NF, Hartley GA, Haukness M, Howe K, Hunkapiller MW, Jain C, Jain M, Jarvis ED, Kerpedjiev P, Kirsche M, Kolmogorov M, Korlach J, Kremitzki M, Li H, Maduro VV, Marschall T, McCartney AM, McDaniel J, Miller DE, Mullikin JC, Myers EW, Olson ND, Paten B, Peluso P, Pevzner PA, Porubsky D, Potapova T, Rogaev EI, Rosenfeld JA, Salzberg SL, Schneider VA, Sedlazeck FJ, Shafin K, Shew CJ, Shumate A, Sims Y, Smit AFA, Soto DC, Sović I, Storer JM, Streets A, Sullivan BA, Thibaud-Nissen F, Torrance J, Wagner J, Walenz BP, Wenger A, Wood JMD, Xiao C, Yan SM, Young AC, Zarate S, Surti U, McCoy RC, Dennis MY, Alexandrov IA, Gerton JL, O'Neill RJ, Timp W, Zook JM, Schatz MC, Eichler EE, Miga KH, Phillippy AM.

Science. 2022 Apr; 6588(376)44-53



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