faculty

Mike Crowder

cmc53@uw.edu
Professor

University of Washington

Anesthesiology

Basic Sciences

Cell Signaling & Cell/Environment Interactions

Genetics, Genomics & Evolution

Neuroscience

Genetic approaches to hypoxic injury in C. elegans

Faculty Contact Information

Building: SLU North Room: N130 Box: 359724 Phone: 206-897-5987 http://depts.washington.edu/mmcslu/faculty/c-michael-crowder-md-phd/

Research Summary

Hypoxia and reoxygenation create havoc in cells. This havoc if unrepaired will ultimately lead to cell dysfunction and death in diseases such as myocardial infarction and stroke. We have taken a relatively underutilized approach of performing forward genetic screens in the nematode C. elegans to discover novel mechanisms of hypoxic injury and protection. We have active projects exploring cell non-autonomous mechanisms of hypoxic injury, identification of new genes and new drugs affecting hypoxic injury, and defining the role of mitochondrial protein misfolding in hypoxic injury and ageing.

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Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter
Permanent

Lab Information

Location: UW SLU
Building: SLU North Building
Room: N130
Box: 359724
http://depts.washington.edu/mmcslu/faculty/c-michael-crowder-md-phd/