Public Health Sciences
Cell Signaling & Cell/Environment Interactions
Developmental Biology, Stem Cells & Aging
Cellular and molecular basis of tumor cell cluster metastasis
Faculty Contact Information
A grand challenge in cancer biology is the problem of metastasis, the process by which tumor cells seed distant organs. Conventional thinking holds that metastases are seeded by single tumor cells, but recent experimental and clinical studies have unveiled the importance of a collective strategy, in which tumor cells efficiently metastasize as clusters. My laboratory pursues the unique questions that emerge from the clustered state. We are particularly intrigued by mechanisms for cell specialization and cooperation, and their implications for metastasis early detection, prognosis, and therapy.
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Building: Arnold Building