Vaccine and Infections Disease Institute
Microbiology, Infection & Immunity
Understanding Protective B cell responses
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Most vaccines provide protection by inducing the production of antibodies that can bind to a pathogen and block infection. Unfortunately, there are many dangerous viruses in which the development of a vaccine has been elusive despite decades of intense research. These failures highlight gaps in knowledge about the type of cell that can produce antibodies, the B cell. The Taylor lab aims to inform vaccine design by gaining a deeper understanding about the mechanisms limiting the generation of a protective B cell response.
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