faculty

Judit Villen

jvillen@uw.edu

Assistant Professor

University of Washington

Genome Sciences

Cancer Biology

Cell Signaling & Cell/Environment Interactions

Cell signaling and Proteomics

Faculty Contact Information

Building: Foege Room: S133C Box: 355065 Phone: 206-685-1490

Research Summary

The Villen lab is interested in the organization principles of signaling. We develop and apply proteomic technologies that provide a systems-level view of signaling to reveal signaling components, their connections, and their functional regulation. Our long-term goal is to understand the wiring diagram of a cell at such resolution that we can predict and control cellular output, encompassing molecules, shapes, and functions.

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Publications

The following publications were retrieved from PubMed:

Regulating Expression of Mistranslating tRNAs by Readthrough RNA Polymerase II Transcription.

Berg MD, Isaacson JR, Cozma E, Genereaux J, Lajoie P, Villén J, Brandl CJ.

ACS Synth Biol. 2021 Nov 19; 11(10)3177-3189

Analysis of Molecular Networks in the Cerebellum in Chronic Schizophrenia: Modulation by Early Postnatal Life Stressors in Murine Models.

Vera-Montecinos A, Rodríguez-Mias R, MacDowell KS, García-Bueno B, Bris ÁG, Caso JR, Villén J, Ramos B.

Int J Mol Sci. 2021 Sep 17; 18(22)

The amino acid substitution affects cellular response to mistranslation.

Berg MD, Zhu Y, Ruiz BY, Loll-Krippleber R, Isaacson J, San Luis BJ, Genereaux J, Boone C, Villén J, Brown GW, Brandl CJ.

G3 (Bethesda). 2021 Sep 27; 10(11)

Elamipretide (SS-31) treatment attenuates age-associated post-translational modifications of heart proteins.

Whitson JA, Martín-Pérez M, Zhang T, Gaffrey MJ, Merrihew GE, Huang E, White CC, Kavanagh TJ, Qian WJ, Campbell MD, MacCoss MJ, Marcinek DJ, Villén J, Rabinovitch PS.

Geroscience. 2021 Oct; 5(43)2395-2412

Decoding Post-Translational Modification Crosstalk With Proteomics.

Leutert M, Entwisle SW, Villén J.

Mol Cell Proteomics. 2021; (20)100129

Accepting Students For:

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Permanent

Lab Information

Location: University of Washington
Building: Foege
Room: S133A
Box: 355065
Phone: 206-543-1880
http://villenlab.gs.washington.edu/