Research Summary
We are interested in molecular processes controlling tissue architecture and morphogenesis in a variety of developmental, physiological, and disease contexts. We study the regulation of cadherin-mediated adhesion across multiple levels; from structural and biochemical mechanisms through cell biological regulation of cell junctions to their impact on physiological and disease processes in vivo. The later include the roles of cadherins in suppressing tumor metastasis and controlling epithelial and endothelial barrier function during inflammation and inflammatory diseases.
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Publications
The following publications were retrieved from PubMed:
