Joseph Mougous


University of Washington, 

Biophysical and Structural Biology

Genetics, Genomics & Evolution

Microbiology, Infection & Immunity

Interbacterial toxins and protein secretion

Faculty Contact Information

Building: Health Sciences Building Room: J-137a Box: 357735 Phone: 206-685-7742 https://microbiology.washington.edu/users/joseph-d-mougous

Lab Information

Location: University of Washington Building: Health Science Building Room: J-135 Box: 357735 Phone: 206-685-6740 http://faculty.washington.edu/mougous/

Accepting Students For:

Rotation, Autumn
Rotation, Spring
Rotation, Summer
Rotation, Winter

Research Summary

We study the interactions of bacteria with each other and with their hosts.  Interbacterial interactions impact humans in many ways, such as whether a given pathogen is able to invade the human gut microbiome. Many interactions between bacteria involve injected toxins. These toxins are fundamentally fascinating molecules, but their study also provides insights into new ways of eradication. Some bacteria secrete factors that directly target host cells. We define and characterize such molecules to understand how environmental bacteria evolve into pathogens of complex organisms.