faculty

Justin Kollman

jkoll@uw.edu

University of Washington,

Biophysical and Structural Biology (Area Director)

Cell Signaling & Cell/Environment Interactions

Microbiology, Infection & Immunity

Structure and function of self-assembling cellular machines

Faculty Contact Information

Building: Health Sciences Building Room: J391 Box: 357350 Phone: 206-543-4051 http://faculty.washington.edu/jkoll/

Lab Information

Location: University of Washington Room: 1959 NE Pacific St. Room J-387 Phone: 206-915-4319 Alt Phone: 2069154319 http://faculty.washington.edu/jkoll/

Accepting Students For:

Rotation, Autumn

Rotation, Spring

Rotation, Summer

Rotation, Winter

Permanent

Research Summary

We use cryo-EM to study the structures of large self assembling macromolecular complexes, including enzyme polymers that regulate cellular metabolism, cytoskeletal structures that organize the intracellular space, and piston-like protein machines that generate force to burst membranes as part of intercellular warfare. In each of these systems protein-protein interactions drive creation of large cellular structures with unique functional properties. We complement our structural work with functional studies using a broad array of biophysical, biochemical, and cell biological approaches.