University of Washington,
Biophysical and Structural Biology
Cell Signaling & Cell/Environment Interactions
Structural study of membrane proteins using cryo-EM
Faculty Contact Information
Accepting Students For:
Our main research interest lies in probing the structures of membrane proteins and their complexes, and understanding the molecular basis of their biological functions. My aim is to establish an infrastructure wherein the structure of any membrane protein including its complexes can be investigated in any functional state. We have developed a novel and general method, called “random spherically constrained” (RSC) single-particle cryo-EM, to study membrane protein structures in membrane environments. Currently, our research focuses on HCN Channel and BK Channel.