University of Washington,
Cell Signaling & Cell/Environment Interactions
Developmental Biology, Stem Cells & Aging
Mechanism and regulation of mitochondrial fusion.
Faculty Contact Information
Mitochondrial membrane fusion is mechanistically unique and poorly understood. Mitochondrial dynamics are essential for mitochondrial function and are also integrated with other processes such as cell cycle progression, cellular immune responses, and apoptotic cell death. Impaired mitochondrial fusion leads to general mitochondrial dysfunction, which has been implicated in several significant public health burdens including Alzheimer’s disease and cancer.
As a mentor I have the opportunity to work with talented students who all have unique career and personal goals. This is a very rewarding aspect of my work. My goal is to facilitate the individual growth of each student as bench scientists and to help develop skills required for their chosen career path. I consider science a team endeavor and diverse teams are always stronger, more creative and more successful. We are lifelong learners in science and in life and I love learning from each other and our unique journeys that brought us to UW.
2019: University of Wisconsin CIMER training on Culturally Aware Mentoring: explored how one’s cultural heritage impacts mentoring
2020: Inclusive teaching and mentoring
2020: Building Healthy Workplaces
2021: Lavender Rights Project: explored LGBTQ+ issues
The following publications were retrieved from PubMed:
Samanas NB, Hoppins S.
Methods Mol Biol. 2020; (2159)129-140
Samanas NB, Engelhart EA, Hoppins S.
Life Sci Alliance. 2020 May; 5(3)
Hoppins S, Lackner LL, Lee JE, Mears JA.
Methods Cell Biol. 2020; (155)491-518
Whitley BN, Engelhart EA, Hoppins S.
Mitochondrion. 2019 Nov; (49)269-283
Sloat SR, Whitley BN, Engelhart EA, Hoppins S.
Mol Biol Cell. 2019 Aug 1; 17(30)2309-2319
Engelhart EA, Hoppins S.
J Biol Chem. 2019 May 17; 20(294)8001-8014
Whitley BN, Lam C, Cui H, Haude K, Bai R, Escobar L, Hamilton A, Brady L, Tarnopolsky MA, Dengle L, Picker J, Lincoln S, Lackner LL, Glass IA, Hoppins S.
Hum Mol Genet. 2018 Nov 1; 21(27)3710-3719
Cunningham CA, Hoppins S, Fink PJ.
J Immunol. 2018 Sep 15; 6(201)1627-1632
Curr Opin Cell Biol. 2014 Aug; (29)46-52
Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J.
J Cell Biol. 2014 Mar 31; 7(204)1083-6
Hoppins S, Nunnari J.
Science. 2012 Aug 31; 6098(337)1052-4
Hoppins S, Collins SR, Cassidy-Stone A, Hummel E, Devay RM, Lackner LL, Westermann B, Schuldiner M, Weissman JS, Nunnari J.
J Cell Biol. 2011 Oct 17; 2(195)323-40
Hoppins S, Edlich F, Cleland MM, Banerjee S, McCaffery JM, Youle RJ, Nunnari J.
Mol Cell. 2011 Jan 21; 2(41)150-60
DeVay RM, Dominguez-Ramirez L, Lackner LL, Hoppins S, Stahlberg H, Nunnari J.
J Cell Biol. 2009 Sep 21; 6(186)793-803
Hoppins S, Horner J, Song C, McCaffery JM, Nunnari J.
J Cell Biol. 2009 Feb 23; 4(184)569-81
Hoppins S, Nunnari J.
Biochim Biophys Acta. 2009 Jan; 1(1793)20-6
Hoppins SC, Go NE, Klein A, Schmitt S, Neupert W, Rapaport D, Nargang FE.
Genetics. 2007 Sep; 1(177)137-49
Hoppins S, Lackner L, Nunnari J.
Annu Rev Biochem. 2007; (76)751-80
Hoppins SC, Nargang FE.
J Biol Chem. 2004 Mar 26; 13(279)12396-405
Mokranjac D, Paschen SA, Kozany C, Prokisch H, Hoppins SC, Nargang FE, Neupert W, Hell K.
EMBO J. 2003 Feb 17; 4(22)816-25
PubMed Collection Link
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