faculty

E Peter Greenberg

epgreen@uw.edu
Professor

University of Washington

Microbiology

Cell Signaling & Cell/Environment Interactions

Genetics, Genomics & Evolution

Microbiology, Infection & Immunity

Bacterial quorum sensing and cooperation

Faculty Contact Information

Building: Health Sciences Room: K 340 Box: 357735 Phone: 206-616-2881 http://depts.washington.edu/epglab/

Research Summary

Dr. Greenberg has spent his scientific career studying microbial social behavior. His particular focus is the area of quorum sensing, a term he introduced into the scientific literature. He has focused on communication and coordination of social activities in Proteobacteria. Bacterial communication controls virulence in a variety of pathogenic bacteria and has thus become a target for development of new therapeutic strategies. Bacteria have also become models for studies of selection for and evolution of cooperative behavior.

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Publications

The following publications were retrieved from PubMed:

Pseudomonas aeruginosa Quorum Sensing.

Miranda SW, Asfahl KL, Dandekar AA, Greenberg EP.

Adv Exp Med Biol. 2022; (1386)95-115

Evolution of the Quorum Sensing Regulon in Cooperating Populations of Pseudomonas aeruginosa.

Smalley NE, Schaefer AL, Asfahl KL, Perez C, Greenberg EP, Dandekar AA.

mBio. 2022 Feb 22; 1(13)e0016122

The Pseudomonas aeruginosa whole genome sequence: A 20th anniversary celebration.

Brinkman FSL, Winsor GL, Done RE, Filloux A, Francis VI, Goldberg JB, Greenberg EP, Han K, Hancock REW, Haney CH, Häußler S, Klockgether J, Lamont IL, Levesque RC, Lory S, Nikel PI, Porter SL, Scurlock MW, Schweizer HP, Tümmler B, Wang M, Welch M.

Adv Microb Physiol. 2021; (79)25-88

A covariation analysis reveals elements of selectivity in quorum sensing systems.

Wellington Miranda S, Cong Q, Schaefer AL, MacLeod EK, Zimenko A, Baker D, Greenberg EP.

Elife. 2021 Jun 28; (10)

Structural basis for a bacterial Pip system plant effector recognition protein.

Luo S, Coutinho BG, Dadhwal P, Oda Y, Ren J, Schaefer AL, Greenberg EP, Harwood CS, Tong L.

Proc Natl Acad Sci U S A. 2021 Mar 9; 10(118)