student

Lori Koch

kochl@uw.edu

Gene Expression, Cell Cycle & Chromosome Biology

Entry Quarter: Autumn 2012

Regulation of the localization and activity of Mps1 kinase at the kinetochore

Defense date: 08/10/2018
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Publications

The following publications were retrieved from PubMed:

Analyzing the genes and pathways related to major depressive disorder via a systems biology approach.

Fan T, Hu Y, Xin J, Zhao M, Wang J.

Brain Behav. 2020 Feb; 2(10)e01502

New discoveries for an old drug: a review of recent olanzapine research.

Meftah AM, Deckler E, Citrome L, Kantrowitz JT.

Postgrad Med. 2020 Jan; 1(132)80-90

Hyperfunctioning thyroid carcinoma: A systematic review.

Liu J, Wang Y, Da D, Zheng M.

Mol Clin Oncol. 2019 Dec; 6(11)535-550

Stem Cell Transplant for Advanced Stage Liver Disorders: Current Scenario and Future Prospects.

Mahmood A, Seetharaman R, Kshatriya P, Patel D, Srivastava AS.

Curr Med Chem. 2019 Oct 4;

The impact of the tax on sweetened beverages: a systematic review.

Redondo M, Hernández-Aguado I, Lumbreras B.

Am J Clin Nutr. 2018 Sep 1; 3(108)548-563



Publications Link

Research Summary

The precise distribution of genetic information during cell division is required for the survival and health of living organisms. Duplicated chromosomes must attach to microtubules via protein complexes called kinetochores to be segregated correctly into the two daughter cells. To ensure genome integrity, the cell has mechanisms to promote and sense productive kinetochore-microtubule (KT-MT) attachments. I am studying how an essential regulator of the KT-MT attachment, a protein kinase called Mps1, localizes to KTs and influences the attachment state.

Lab Information

Advisor: Sue Biggins
Box: 357275
206-667-5766