student

Anna-Lisa Doebley

adoebley@uw.edu

Cancer Biology

Computational Biology

Genetics, Genomics & Evolution

Entry Quarter: Spring 2017
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Publications

The following publications were retrieved from PubMed:

The meiotic phosphatase GSP-2/PP1 promotes germline immortality and small RNA-mediated genome silencing.

Billmyre KK, Doebley AL, Spichal M, Heestand B, Belicard T, Sato-Carlton A, Flibotte S, Simon M, Gnazzo M, Skop A, Moerman D, Carlton PM, Sarkies P, Ahmed S.

PLoS Genet. 2019 Mar; 3(15)e1008004

The effect of Tmem135 overexpression on the mouse heart.

Lewis SA, Takimoto T, Mehrvar S, Higuchi H, Doebley AL, Stokes G, Sheibani N, Ikeda S, Ranji M, Ikeda A.

PLoS One. 2018; 8(13)e0201986

denovo-db: a compendium of human de novo variants.

Turner TN, Yi Q, Krumm N, Huddleston J, Hoekzema K, F Stessman HA, Doebley AL, Bernier RA, Nickerson DA, Eichler EE.

Nucleic Acids Res. 2017 Jan 4; D1(45)D804-D811

Caenorhabditis elegans RSD-2 and RSD-6 promote germ cell immortality by maintaining small interfering RNA populations.

Sakaguchi A, Sarkies P, Simon M, Doebley AL, Goldstein LD, Hedges A, Ikegami K, Alvares SM, Yang L, LaRocque JR, Hall J, Miska EA, Ahmed S.

Proc Natl Acad Sci U S A. 2014 Oct 14; 41(111)E4323-31

Reduced insulin/IGF-1 signaling restores germ cell immortality to Caenorhabditis elegans Piwi mutants.

Simon M, Sarkies P, Ikegami K, Doebley AL, Goldstein LD, Mitchell J, Sakaguchi A, Miska EA, Ahmed S.

Cell Rep. 2014 May 8; 3(7)762-73

Research Summary

I’m interested in using computational methods to improve cancer detection, prognosis, and treatment. In the Ha lab, I am developing and applying novel approaches to analyze cell-free DNA from advanced cancer patients.

Lab Information

Advisor: Gavin Ha
Co-Advisor: David MacPherson