student

Stephen Rettie

srettie@uw.edu

University of Washington

Medical Chemistry

Biophysical and Structural Biology

Computational Biology

Microbiology, Infection & Immunity

Entry Quarter: Autumn 2019
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Publications

The following publications were retrieved from PubMed:

Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites.

Hosseinzadeh P, Watson PR, Craven TW, Li X, Rettie S, Pardo-Avila F, Bera AK, Mulligan VK, Lu P, Ford AS, Weitzner BD, Stewart LJ, Moyer AP, Di Piazza M, Whalen JG, Greisen PJ, Christianson DW, Baker D.

Nat Commun. 2021 Jun 7; 1(12)3384

Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1.

Mulligan VK, Workman S, Sun T, Rettie S, Li X, Worrall LJ, Craven TW, King DT, Hosseinzadeh P, Watkins AM, Renfrew PD, Guffy S, Labonte JW, Moretti R, Bonneau R, Strynadka NCJ, Baker D.

Proc Natl Acad Sci U S A. 2021 Mar 23; 12(118)

Computational design of mixed chirality peptide macrocycles with internal symmetry.

Mulligan VK, Kang CS, Sawaya MR, Rettie S, Li X, Antselovich I, Craven TW, Watkins AM, Labonte JW, DiMaio F, Yeates TO, Baker D.

Protein Sci. 2020 Dec; 12(29)2433-2445

Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides.

Buchko GW, Pulavarti SVSRK, Ovchinnikov V, Shaw EA, Rettie SA, Myler PJ, Karplus M, Szyperski T, Baker D, Bahl CD.

Protein Sci. 2018 Sep; 9(27)1611-1623

Comprehensive computational design of ordered peptide macrocycles.

Hosseinzadeh P, Bhardwaj G, Mulligan VK, Shortridge MD, Craven TW, Pardo-Avila F, Rettie SA, Kim DE, Silva DA, Ibrahim YM, Webb IK, Cort JR, Adkins JN, Varani G, Baker D.

Science. 2017 Dec 15; 6369(358)1461-1466



Publications Link

Lab Information

Advisor: Gaurav Bhardwaj