Sarah Waldherr


Entry Quarter: Summer 2014

Research Summary

I am investigating the role of the endoplasmic reticulum unfolded protein response in neurodegenerative diseases with tau pathology. Specifically, I am using tau transgenic C. elegans to study suppression of tau toxicity when XBP-1s is hyperactivated. I will also determine whether this translates to mammalian systems using human cell culture models and mouse models.

Lab Information

Advisor: Brian Kraemer
Box: 357275