Microbiology, Infection & Immunity
Defining mechanisms of disease initiation through analysis of Helicobacter pylori interactions with gastric microbial communities and the host
The following publications were retrieved from PubMed:
Bauer M, Nascakova Z, Mihai AI, Cheng PF, Levesque MP, Lampart S, Hurwitz R, Pfannkuch L, Dobrovolna J, Jacobs M, Bartfeld S, Dohlman A, Shen X, Gall AA, Salama NR, Töpfer A, Weber A, Meyer TF, Janscak P, Müller A.
Nat Commun. 2020 Oct 9; 1(11)5117
Gall A, Gaudet RG, Gray-Owen SD, Salama NR.
mBio. 2017 Aug 15; 4(8)
Gall A, Fero J, McCoy C, Claywell BC, Sanchez CA, Blount PL, Li X, Vaughan TL, Matsen FA, Reid BJ, Salama NR.
PLoS One. 2015; 6(10)e0129055
Gall A, Treuting P, Elkon KB, Loo YM, Gale M Jr, Barber GN, Stetson DB.
Immunity. 2012 Jan 27; 1(36)120-31
Gall A, Horowitz A, Joof H, Natividad A, Tetteh K, Riley E, Bailey RL, Mabey DC, Holland MJ.
Front Microbiol. 2011; (2)10
Holland MJ, Jeffries D, Pattison M, Korr G, Gall A, Joof H, Manjang A, Burton MJ, Mabey DC, Bailey RL.
Invest Ophthalmol Vis Sci. 2010 Aug; 8(51)3893-902
I am interested in understanding how the gastric pathogen, Helicobacter pylori , interacts with its host. My projects are focused on elucidating the cellular and molecular mechanisms by which H. pylori triggers an innate immune response in gastric epithelial cells through the intracellular delivery of bacterial virulence factors into the host cell. Additionally, I am developing new tools for studying this host-pathogen interaction through the use of gastric organoid cell culture.