student
Brittany Whitley
whitleyb@uw.eduUniversity of Washington
,Biochemistry
Cell Signaling & Cell/Environment Interactions
Developmental Biology, Stem Cells & Aging
Entry
Quarter: Autumn 2014
Characterizing the molecular mechanisms that maintain balanced mitochondrial fusion and division in healthy and diseased cells
Defense date: 08/05/2019
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Publications
The following publications were retrieved from PubMed:
Morell RJ, Olszewski R, Tona R, Leitess S, Wafa TT, Taukulis I, Schultz JM, Thomason EJ, Richards K, Whitley BN, Hill C, Saunders T, Starost MF, Fitzgerald T, Wilson E, Ohyama T, Friedman TB, Hoa M.
J Neurosci. 2020 Apr 8; 15(40)2976-2992
Mitochondrial dynamics and their potential as a therapeutic target.
Whitley BN, Engelhart EA, Hoppins S.
Mitochondrion. 2019 Nov; (49)269-283
Identification of a mitofusin specificity region that confers unique activities to Mfn1 and Mfn2.
Sloat SR, Whitley BN, Engelhart EA, Hoppins S.
Mol Biol Cell. 2019 Aug 1; 17(30)2309-2319
Aberrant Drp1-mediated mitochondrial division presents in humans with variable outcomes.
Whitley BN, Lam C, Cui H, Haude K, Bai R, Escobar L, Hamilton A, Brady L, Tarnopolsky MA, Dengle L, Picker J, Lincoln S, Lackner LL, Glass IA, Hoppins S.
Hum Mol Genet. 2018 Nov 1; 21(27)3710-3719
Davis MY, Trinh K, Thomas RE, Yu S, Germanos AA, Whitley BN, Sardi SP, Montine TJ, Pallanck LJ.
PLoS Genet. 2016 Mar; 3(12)e1005944
Fletcher KL, Whitley BN, Treidel LA, Thompson D, Williams A, Noguera JC, Stevenson JR, Haussmann MF.
Biol Lett. 2015 Jul; 7(11)
Treidel LA, Whitley BN, Benowitz-Fredericks ZM, Haussmann MF.
Biol Lett. 2013 Oct 23; 5(9)20130684
Research Summary
I study regulation of the mitochondrial outer membrane fusion proteins, Mfn1 and Mfn2.
Lab Information
Advisor: Suzanne Hoppins