student

Adam Dingens

adingens@uw.edu

Microbiology, Infection & Immunity

Entry Quarter: Autumn 2013

Complete mapping of HIV-1 escape from broadly neutralizing antibodies, vaccines, and drugs

Defense date: 01/07/2019
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&query_key=1&WebEnv=MCID_5fc1134af631753c200603d7&retmode=json
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Publications

The following publications were retrieved from PubMed:

Dynamics of neutralizing antibody titers in the months after SARS-CoV-2 infection.

Crawford KHD, Dingens AS, Eguia R, Wolf CR, Wilcox N, Logue JK, Shuey K, Casto AM, Fiala B, Wrenn S, Pettie D, King NP, Greninger AL, Chu HY, Bloom JD.

J Infect Dis. 2020 Sep 30;

Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition.

Greaney AJ, Starr TN, Gilchuk P, Zost SJ, Binshtein E, Loes AN, Hilton SK, Huddleston J, Eguia R, Crawford KHD, Dingens AS, Nargi RS, Sutton RE, Suryadevara N, Rothlauf PW, Liu Z, Whelan SPJ, Carnahan RH, Crowe JE, Bloom JD.

bioRxiv. 2020 Sep 10;

Serological identification of SARS-CoV-2 infections among children visiting a hospital during the initial Seattle outbreak.

Dingens AS, Crawford KHD, Adler A, Steele SL, Lacombe K, Eguia R, Amanat F, Walls AC, Wolf CR, Murphy M, Pettie D, Carter L, Qin X, King NP, Veesler D, Krammer F, Dickerson JA, Chu HY, Englund JA, Bloom JD.

Nat Commun. 2020 Sep 1; 1(11)4378

Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding.

Starr TN, Greaney AJ, Hilton SK, Ellis D, Crawford KHD, Dingens AS, Navarro MJ, Bowen JE, Tortorici MA, Walls AC, King NP, Veesler D, Bloom JD.

Cell. 2020 Sep 3; 5(182)1295-1310.e20

Neutralizing Antibodies Correlate with Protection from SARS-CoV-2 in Humans during a Fishery Vessel Outbreak with a High Attack Rate.

Addetia A, Crawford KHD, Dingens A, Zhu H, Roychoudhury P, Huang ML, Jerome KR, Bloom JD, Greninger AL.

J Clin Microbiol. 2020 Oct 21; 11(58)

Research Summary

I am developing new approaches to comprehensively map viral escape from anti-HIV antibodies, and using such approaches to interrogate Env function and evolution.

Lab Information

Advisor: Julie Overbaugh
Co-Advisor: Jesse Bloom