student

Pia Hoellerbauer

hoellp@uw.edu

Cancer Biology

Developmental Biology, Stem Cells & Aging

Entry Quarter: Autumn 2013
Defense date: 03/10/2020
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&query_key=1&WebEnv=MCID_6391530b3a7966776a77a213&retmode=json
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Publications

The following publications were retrieved from PubMed:

Hyper-active RAS/MAPK introduces cancer-specific mitotic vulnerabilities.

Herman JA, Romain RR, Hoellerbauer P, Shirnekhi HK, King DC, DeLuca KF, Osborne Nishimura E, Paddison PJ, DeLuca JG.

Proc Natl Acad Sci U S A. 2022 Oct 11; 41(119)e2208255119

Neural G0: a quiescent-like state found in neuroepithelial-derived cells and glioma.

O'Connor SA, Feldman HM, Arora S, Hoellerbauer P, Toledo CM, Corrin P, Carter L, Kufeld M, Bolouri H, Basom R, Delrow J, McFaline-Figueroa JL, Trapnell C, Pollard SM, Patel A, Paddison PJ, Plaisier CL.

Mol Syst Biol. 2021 Jun; 6(17)e9522

Efficient Multi-Allelic Genome Editing of Primary Cell Cultures via CRISPR-Cas9 Ribonucleoprotein Nucleofection.

Hoellerbauer P, Kufeld M, Paddison PJ.

Curr Protoc Stem Cell Biol. 2020 Sep; 1(54)e126

A simple and highly efficient method for multi-allelic CRISPR-Cas9 editing in primary cell cultures.

Hoellerbauer P, Kufeld M, Arora S, Wu HJ, Feldman HM, Paddison PJ.

Cancer Rep (Hoboken). 2020 Oct; 5(3)e1269

Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis.

Szulzewsky F, Arora S, Hoellerbauer P, King C, Nathan E, Chan M, Cimino PJ, Ozawa T, Kawauchi D, Pajtler KW, Gilbertson RJ, Paddison PJ, Vasioukhin V, Gujral TS, Holland EC.

Genes Dev. 2020 Aug 1; 15-16(34)1051-1064

Research Summary

I use functional genomic screening in glioblastoma cancer stem-like cells and normal neural stem cells (a non-transformed control) in order to identify genes that are selectively required for the survival of cancer stem-like cells. Such genes represent promising novel therapeutic targets.

Lab Information

Advisor: Patrick Paddison
206-667-6020