Matt Kaeberlein
kaeber@uw.eduUniversity of Washington,
Developmental Biology, Stem Cells & Aging (Area Director)
Genetics, Genomics & Evolution
Basic and translational geroscience (biology of aging)
Faculty Contact Information
Lab Information
Accepting Students For:
Publications
Improving Precursor Selectivity in Data-Independent Acquisition Using Overlapping Windows.
Amodei D, Egertson J, MacLean BX, Johnson R, Merrihew GE, Keller A, Marsh D, Vitek O, Mallick P, MacCoss MJ.
Journal of the American Society for Mass Spectrometry. 2019; 30(4):669-684.
- PMID:
- 30671891
- PMCID:
- PMC6445824
Lee MB, Dowsett IT, Carr DT, Wasko BM, Stanton SG, Chung MS, Ghodsian N, Bode A, Kiflezghi MG, Uppal PA, Grayden KA, Elala YC, Tang TT, Tran NHB, Tran THB, Diep AB, Hope M, Promislow DEL, Kennedy SR, Kaeberlein M, Herr AJ.
Proceedings of the National Academy of Sciences of the United States of America. 2019; 116(8):3062-3071.
- PMID:
- 30718408
- PMCID:
- PMC6386679
Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast.
Beaupere C, Dinatto L, Wasko BM, Chen RB, VanValkenburg L, Kiflezghi MG, Lee MB, Promislow DEL, Dang W, Kaeberlein M, Labunskyy VM.
Proceedings of the National Academy of Sciences of the United States of America. 2018; 115(38):9586-9591.
- PMID:
- 30185560
- PMCID:
- PMC6156608
How healthy is the healthspan concept?
Kaeberlein M.
GeroScience. 2018; 40(4):361-364.
- PMID:
- 30084059
- PMCID:
- PMC6136295
Burnaevskiy N, Chen S, Mailig M, Reynolds A, Karanth S, Mendenhall A, Van Gilst M, Kaeberlein M.
eLife. 2018; 7.
- PMID:
- 30070633
- PMCID:
- PMC6089596
Crane MM, Kaeberlein M.
Current opinion in systems biology. 2018; 8:25-31. NIHMSID: NIHMS925979
- PMID:
- 29552673
- PMCID:
- PMC5851462
Oral health in geroscience: animal models and the aging oral cavity.
An JY, Darveau R, Kaeberlein M.
GeroScience. 2018; 40(1):1-10.
- PMID:
- 29282653
- PMCID:
- PMC5832657
Genetic interaction with temperature is an important determinant of nematode longevity.
Miller H, Fletcher M, Primitivo M, Leonard A, Sutphin GL, Rintala N, Kaeberlein M, Leiser SF.
Aging cell. 2017; 16(6):1425-1429.
- PMID:
- 28940623
- PMCID:
- PMC5676069
Russell JC, Burnaevskiy N, Ma B, Mailig MA, Faust F, Crane M, Kaeberlein M, Mendenhall A.
The journals of gerontology. Series A, Biological sciences and medical sciences. 2017;
- PMID:
- 29165668
- PMCID:
- PMC6625588
Mukherjee S, Russell JC, Carr DT, Burgess JD, Allen M, Serie DJ, Boehme KL, Kauwe JSK, Naj AC, Fardo DW, Dickson DW, Montine TJ, Ertekin-Taner N, Kaeberlein MR, Crane PK.
Alzheimer's & dementia : the journal of the Alzheimer's Association. 2017; 13(10):1133-1142. NIHMSID: NIHMS883971
- PMID:
- 28242297
- PMCID:
- PMC5568992
Research Summary
Age is the single greatest risk factor for nearly every major cause of morbidity and mortality in developed nations: Alzheimer’s disease, heart disease, most cancers, diabetes, kidney disease, etc. The Kaeberlein lab is interested in understanding the molecular mechanisms that drive the aging process and cause people to develop diseases and disabilities of aging. We hope to use this information to directly intervene in the aging process in order to promote healthy longevity.