Cell Signaling & Cell/Environment Interactions
Genetics, Genomics & Evolution
Faculty Contact Information
Molecular conversations between glia and neurons, the two major cells of our nervous system, are critical to all aspects of nervous system biology. However, while defects in glia-neuron interactions link to many neurological diseases, they remain largely enigmatic at molecular resolution.
Our lab aims to define molecular mechanisms of glia-neuron interactions in health, aging and disease models. For this, we deploy techniques at multiple focus levels, from molecular genetic, -omic, biochemical) to cell-biology (various microscopy) and animal behavior studies, as needed.
Biases are neither binary nor limited to one issue or culture. My commitment to an inclusive and egalitarian lab is deliberate. I pledge to being a constant ally, advocate and listener, and for the lab to be a safe space for all. Our lab aims to grow and learn together as a team, and consciously strive to do more and do better by each other.
We are a team of diverse individuals that support, enable and take pride in each other. As a mentor, I aim to listen and adapt to provide meaningful, individually tailored mentor-ship. My goal is to to support and guide trainees to achieve their full potential and goals that they set for themselves & beyond. Every lab alumnus thus far has successfully transitioned into the career phase they had aspired for, including PhD, MD-PhD, and postdoctoral fellowship.
Faculty Mentorship Training (HHMI-Gilliam) – 2020-2023
Bias Mitigation Education Training Module (Fred Hutch) – 2021
Faculty Advisory Committee, Office on Diversity and Inclusion, Fred Hutch – 2018-Present
Strategic Planning Committee, The Rockefeller University Diversity Initiative (represent all trainees) – 2015-2018
The following publications were retrieved from PubMed:
Ackerman SD, Singhvi A, Bianchi L.
Front Neurosci. 2022; (16)965580
Raiders S, Klein M, Singhvi A.
Bio Protoc. 2022 Apr 5; 7(12)e4370
Ray S, Singhvi A.
Front Cell Dev Biol. 2021; (9)687732
Raiders S, Black EC, Bae A, MacFarlane S, Klein M, Shaham S, Singhvi A.
Elife. 2021 Mar 24; (10)
Raiders S, Han T, Scott-Hewitt N, Kucenas S, Lew D, Logan MA, Singhvi A.
J Neurosci. 2021 Feb 3; 5(41)823-833
Gourgou E, Willis AR, Giunti S, De Rosa MJ, Charlesworth AG, Hernandez Lima M, Glater E, Soo S, Pereira B, Akbaş K, Deb A, Kamak M, Moyle MW, Traa A, Singhvi A, Sural S, Jin EJ.
J Neurogenet. 2020 Sep-Dec; 3-4(34)549-560
Huang TT, Matsuyama HJ, Tsukada Y, Singhvi A, Syu RT, Lu Y, Shaham S, Mori I, Pan CL.
Aging Cell. 2020 May; 5(19)e13146
Singhvi A, Shaham S.
Annu Rev Neurosci. 2019 Jul 8; (42)149-168
Wallace SW, Singhvi A, Liang Y, Lu Y, Shaham S.
Cell Rep. 2016 Apr 19; 3(15)550-562
Singhvi A, Liu B, Friedman CJ, Fong J, Lu Y, Huang XY, Shaham S.
Cell. 2016 May 5; 4(165)936-48
Teuliere J, Cordes S, Singhvi A, Talavera K, Garriga G.
Genetics. 2014 Sep; 1(198)229-47
Singhvi A, Teuliere J, Talavera K, Cordes S, Ou G, Vale RD, Prasad BC, Clark SG, Garriga G.
Curr Biol. 2011 Jun 7; 11(21)948-54
Singhvi A, Sachdev P.
Nat Biotechnol. 2010 Apr; 4(28)378-9
Singhvi A, Garriga G.
Trends Cell Biol. 2009 Jan; 1(19)1-7
Singhvi A, Frank CA, Garriga G.
Genetics. 2008 Jun; 2(179)887-98
Wang Z, Singhvi A, Kong P, Scott K.
Cell. 2004 Jun 25; 7(117)981-91
PubMed Collection Link