Microbiology, Infection & Immunity
Immunity to viral infections and pre-clinical and clinical vaccine testing
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Dr. Stamatatos’s Lab monitors the activation, survival, and maturation of B cell clonal lineages that produce protective antibodies against infectious agents. Immunogens and immunization regiments are developed to target these B cell lineages in vivo. The Lab employs diverse experimental approaches, including structure-based immunogen-design, X-ray crystallography, next generation deep sequencing, and immunological, molecular, and cellular techniques. The Lab’s work encompasses the entire space between pre-clinical and clinical evaluation of candidate vaccines.