faculty

Ben Kerr

kerrb@uw.edu
Professor

University of Washington

Biology

Computational Biology

Genetics, Genomics & Evolution

Microbiology, Infection & Immunity

Microbial experimental evolution and evolutionary modeling

Faculty Contact Information

Building: Kincaid Room: 404 Box: Box 351800 Phone: 206-221-3996 http://kerrlab.org/

Research Summary

Biological systems are teeming with interactions. For instance, species interact in ecosystems, nerve cells interact in brains, and genes interact in regulatory networks. Similarly, genetic mutation does not occur in a vacuum: the selective value of any mutation for an organism may depend on its genetic background and its ecological conditions. When the fitness effect of a mutation changes with genotype (epistasis) or environment (pleiotropy), evolution becomes contingent. Our lab is focused on understanding such contingency and using this information to our benefit in health-related contexts.

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Publications

The following publications were retrieved from PubMed:

The Role of Pleiotropy in the Evolutionary Maintenance of Positive Niche Construction.

Chisholm RH, Connelly BD, Kerr B, Tanaka MM.

Am Nat. 2018 Jul; 1(192)35-48

Adaptations of an RNA virus to increasing thermal stress.

Singhal S, Leon Guerrero CM, Whang SG, McClure EM, Busch HG, Kerr B.

PLoS One. 2017; 12(12)e0189602

Replication and shedding kinetics of infectious hematopoietic necrosis virus in juvenile rainbow trout.

Wargo AR, Scott RJ, Kerr B, Kurath G.

Virus Res. 2017 Jan 2; (227)200-211

Transitions in individuality through symbiosis.

Estrela S, Kerr B, Morris JJ.

Curr Opin Microbiol. 2016 Jun; (31)191-198

Lab Information

Location: University of Washington
Building: Kincaid
Room: 404
Box: Box 351800
http://kerrlab.org/