student

Cassandra Simonich

abelca@uw.edu

Microbiology, Infection & Immunity

Entry Quarter: Autumn 2013

Isolation and characterization of HIV-1 neutralizing antibodies from infants

Defense date: 05/22/2018
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&query_key=1&WebEnv=MCID_62884ca0728f5c54bb7a40ee&retmode=json
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Publications

The following publications were retrieved from PubMed:

A diverse collection of B cells responded to HIV infection in infant BG505.

Simonich C, Shipley MM, Doepker L, Gobillot T, Garrett M, Cale EM, Hennessy B, Itell H, Chohan V, Doria-Rose N, Nduati R, Overbaugh J.

Cell Rep Med. 2021 Jun 15; 6(2)100314

Diversity and Function of Maternal HIV-1-Specific Antibodies at the Time of Vertical Transmission.

Doepker LE, Simonich CA, Ralph D, Shipley MM, Garrett M, Gobillot T, Vigdorovich V, Sather DN, Nduati R, Matsen FA 4th, Overbaugh JM.

J Virol. 2020 Apr 16; 9(94)

Kappa chain maturation helps drive rapid development of an infant HIV-1 broadly neutralizing antibody lineage.

Simonich CA, Doepker L, Ralph D, Williams JA, Dhar A, Yaffe Z, Gentles L, Small CT, Oliver B, Vigdorovich V, Mangala Prasad V, Nduati R, Sather DN, Lee KK, Matsen Iv FA, Overbaugh J.

Nat Commun. 2019 May 16; 1(10)2190

Superinfection Drives HIV Neutralizing Antibody Responses from Several B Cell Lineages that Contribute to a Polyclonal Repertoire.

Williams KL, Wang B, Arenz D, Williams JA, Dingens AS, Cortez V, Simonich CA, Rainwater S, Lehman DA, Lee KK, Overbaugh J.

Cell Rep. 2018 Apr 17; 3(23)682-691

Epitope-Independent Purification of Native-Like Envelope Trimers from Diverse HIV-1 Isolates.

Verkerke HP, Williams JA, Guttman M, Simonich CA, Liang Y, Filipavicius M, Hu SL, Overbaugh J, Lee KK.

J Virol. 2016 Oct 15; 20(90)9471-82



Publications Link

Research Summary

My graduate research focuses on the isolation and study of infant HIV-1 neutralizing antibodies.

Lab Information

Advisor: Julie Overbaugh
206-667-4510